Category: Combinatorial optimization

Personal web page of Marco S. Nobile, Associate Professor with the Ca' Foscari University of Venice, Italy

New paper about Dynamic Fuzzy Modeling accepted on Bioinformatics

Many years ago we started a cooperation with the Department of Biotechnology and Biosciences of the University of Milano-Bicocca. The goal was to govern programmed cell death on K-ras cancer cells under conditions of glucose starvation. Glucose is directly related to metabolism, i.e., glycolysis and TCA cycle in mitochondria, which in turn determine the production …

GenHap, a novel evolutionary approach for haplotyping, published on BMC Bioinformatics

GenHap is a novel evolutionary method to solve the haplotyping problem. basically subdivides the data into multiple independent combinatorial subproblems, each solved using a separate genetic algorithm. Then a recombination step fuses the solutions of subproblems into a final complete haplotype. GenHap also natively distributes the calculations over multiple cores by means of MPI, reducing …