Category: Combinatorial optimization

Marco S. Nobile, Associate Professor with the Ca' Foscari University of Venice, Italy

New paper about Dynamic Fuzzy Modeling accepted on Bioinformatics

Many years ago we started a cooperation with the Department of Biotechnology and Biosciences of the University of Milano-Bicocca. The goal was to govern programmed cell death on K-ras cancer cells under conditions of glucose starvation. Glucose is directly related to metabolism, i.e., glycolysis and TCA cycle in mitochondria, which in turn determine the production …

GenHap, a novel evolutionary approach for haplotyping, published on BMC Bioinformatics

GenHap is a novel evolutionary method to solve the haplotyping problem. basically subdivides the data into multiple independent combinatorial subproblems, each solved using a separate genetic algorithm. Then a recombination step fuses the solutions of subproblems into a final complete haplotype. GenHap also natively distributes the calculations over multiple cores by means of MPI, reducing …