Category: Complexity

New paper on Scientific Reports

Self-assembling peptides can be useful for clinical applications, for instance as scaffolds based on beta-sheets motifs. The dynamic evolution and self-assemly of peptide systems can be investigated in silico by using molecular dynamics. In particular, coarse-grained simulation exploiting MARTINI force fields can strongly reduce the overall running time and still provide useful information. In a …

New paper about Dynamic Fuzzy Modeling accepted on Bioinformatics

Many years ago we started a cooperation with the Department of Biotechnology and Biosciences of the University of Milano-Bicocca. The goal was to govern programmed cell death on K-ras cancer cells under conditions of glucose starvation. Glucose is directly related to metabolism, i.e., glycolysis and TCA cycle in mitochondria, which in turn determine the production …

New paper accepted on IEEE Transactions on Fuzzy Systems

We use Fuzzy Logic to create interpretable models of heterogeneous cellular systems characterized by uncertainty…